Simulating enzyme reactions: Challenges and perspectives
نویسنده
چکیده
Elucidating how enzymes enhance the rates of the reactions that they catalyze is a major goal of contemporary biochemistry, and it is an area in which computational and theoretical techniques can make a major contribution. This article outlines some of the processes that need to be investigated if enzyme catalysis is to be understood, reviews the current state-of-the-art in enzyme simulation work, and highlights challenges for the future.
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ورودعنوان ژورنال:
- Journal of computational chemistry
دوره 23 1 شماره
صفحات -
تاریخ انتشار 2002